Gr诺p Ymchwil Economeg, Polisi a Phresgripsiynu Fferyllol - Allbynnau Ymchwil
Rhannwch y dudalen hon
Cyhoeddiadau ac Adroddiadau
2025
Sinnappah KA, Hughes DA (2025), Stocker SL, Wright DFB; ESPACOMP the International Society for Medication Adherence. Risk of bias tools for medication adherence research: RoBIAS and RoBOAS. Br J Clin Pharmacol.
2024
Pijeira Perez Y, Hughes DA (2024). Evidence Following Conditional NICE Technology Appraisal Recommendations: A Critical Analysis of Methods, Quality and Risk of Bias. Pharmacoeconomics. 42(12): 1373-1394. https//:doi.org/10.1007/s40273-024-01418-3
Holmes, E., Arkesteijn, M., Knowles, K., McKinney, T., Mizen, A., & Purcell, C. (2024). Understanding the interactions that children and young people have with their natural and built environments: A survey to identify targets for active travel behaviour change in Wales. PLoS ONE, 19(10), Article e0311498.
Opatola AV, Seaborne MJ, Kennedy J, Hughes D, Laing H, Owen RK, Tuthill D, Bracchi R, Brophy S (2024). Association of child weight and adverse outcomes following antibiotic prescriptions in children: a national data study in Wales, UK. BMJ Paediatr Open. 8(1):e002831.
Michael, T. J. F., Wright, D. F. B., Chan, J. S., Coleshill, M. J., Aslani, P., Hughes, D., Day, R. O., & Stocker, S. L. (2024). Patient-led urate self-monitoring to improve clinical outcomes in people with gout: a feasibility study. ACR Open Rheumatology, 6(7), 403-411.
Chebib, N. Holmes, E., Maniewicz, S., Abou-Ayash, S., Srinivasan, M., McKenna, G., Kossioni, A., Schimmel, M., Muller, F., & Brocklehurst, P. (2024). Exploring preferences of older adults for dental services: A pilot multi-national discrete choice experiment. Gerodontology, 41(2), 220-230.
Anthony, B., Davies, J., Pisavadia, K.,Roberts, S., Spencer, L. H., Gillen, E., Hounsome, J. Noyes, J.,Hughes, D., Fitzsimmons, D., Edwards, R. T, Edwards, A., Cooper, A. & Lewis, R. (2024). The clinical and cost-effectiveness of interventions for preventing continence issues resulting from birth trauma: a rapid review. MedRxiv.
Totton, N., Waddingham, E., Owen, R., Julious, S., Hughes, D., & Cook, J. (2024). A proposal for using benefit-risk methods to improve the prominence of adverse event results when reporting trials. Trials, 25, Article 409.
Charlton, V., diStefano, M., Mitchell, P., Morrell, L., Rand, L., Badano, G., Baker, R., Calnan, M., Chalkidou, K., Culyer, A., Howden, D., Hughes, D., Lomas, J., Max, C., McCabe, C., O'Mahony, J. F., Paulden, M., Pemberton-Whiteley, Z., Rid, A., & Wester, G. (2024). We need to talk about values: a proposed framework for the articulation of normative reasoning in health technology assessment. Health Economics, Policy and Law, 19(2), 153-173.
Noble, A. J., Dixon, P., Mathieson, A., Ridsdale, L., Morgan, M., McKinlay, A., Dickson, J., Goodacre, S., Jackson, M., Morris, B., Hughes, D., Marson, T., & Holmes, E. (2024). Developing feasible person-centred care alternatives to emergency department responses for adults with epilepsy: a discrete choice analysis mixed methods study. Health Services and Delivery Research (HS&DR), 12(24).
Culeddu, G., Cividini, S., Sinha, I., Donegan, S., Maden, M., Rose, K., Fulton, O., Turner, S., Smith, C. T., & Hughes, D. (2024). Economic analysis of treatments for children who do not achieve adequate asthma control when using low-dose inhaled corticosteroids. Disease in Childhood, 109(suppl 1).
Holmes, E., Williams, H., Hughes, D., Naujokat, E., Duller, B. & Subbe, C. (2024). A model-based cost-utility analysis of an automated notification system for deteriorating patients on general wards. PLOS ONE journal.
Michael, T. J. F., Wright, D. F. B., Chan, J. S., Coleshill, M. J., Aslani, P., Hughes, D., Day, R. O. & Stocker, S. L. (2024). The experiences and perspectives of people with gout on urate self-monitoring. In: ACR Open Rheumatology.
Holmes, E., Dixon, P., Mathieson, A., Ridsdale, L., Morgan, M., McKinlay, A., Dickson, J., Goodacre, S., Jackson, M., Foster, D., Hardman, K., Bell, S., Marson, A., Hughes, D. & Noble, A. J. (2024). Developing an alternative care pathway for emergency ambulance responses for adults with epilepsy: A Discrete Choice Experiment to understand which configuration service users prefer. Part of the COLLABORATE project. Seizure: European Journal of Epilepsy. 118, p. 28-37.
Noble, A. J., Morris, B., Dixon, P., Mathieson, A., Ridsdale, L., Morgan, M., Dickson, J., Goodacre, S., Jackson, M., Hughes, D., Marson, A. & Holmes, E. (2024). Service users' preferences and feasibility 鈥 which alternative care pathway for adult ambulance users achieves the optimal balance? Workshops for the COLLABORATE project. Seizure: European Journal of Epilepsy. 118, p. 17-27.
Hassan, A, Davies, N. (2024). Expert Insight Into the Use of eHealth Interventions to Aid Medication Adherence During COVID-19. Patient Preference and Adherence. 18, p. 721-731 11 p.
Spencer, L., Anthony, B., Davies, J., Pisavadia, K., Gillen, E., Noyes, J., Fitzsimmons, D., Lewis, R., Cooper, A., Hughes, D., Edwards, R. T. & Edwards, A. (2024). The costs and cost-effectiveness of different service models of palliatice care, focusing on end of life care: A rapid review. 7 Mar 2024, MedRxiv, 118 p.
Michael, T. J. F., Wright, D. F. B., Chan, J. S., Coleshill, M. J., Aslani, P., Hughes, D., Day, R. O. & Stocker, S. L. (2024). Patient-led urate self-monitoring to improve clinical outcomes in people with gout: a feasibility study. 21 Feb 2024, In: ACR Open Rheumatology.
SuMMiT-D Collaborative Group. (2024). Supporting people with type 2 diabetes in effective use of their medicine through mobile health technology integrated with clinical care (SuMMiT-D pilot): results of a feasibility randomised trial. 25 Jan 2024. Pilot and Feasibility Studies. 10, 1, 15.
2023
Charlton V, DiStefano M, Mitchell P, Morrell L, Rand L, Badano G, Baker R, Calnan M, Chalkidou K, Culyer A, Howdon D, Hughes D, Lomas J, Max C, McCabe C, O'Mahony JF, Paulden M, Pemberton-Whiteley Z, Rid A, Scuffham P, Sculpher M, Shah K, Weale A, Wester G. (2023). We need to talk about values: a proposed framework for the articulation of normative reasoning in health technology assessment. Health Econ Policy Law. 2023 Sep 27:1-21. .
Cividini S, Sinha I, Donegan S, Maden M, Rose K, Fulton O, Culeddu G, Hughes DA, Turner S, Tudur Smith C. (2023). On behalf of the EINSTEIN collaborative group. Best step-up treatments for children with uncontrolled asthma: A systematic review and network meta-analysis of individual participant data. Eur Respir J. 2023 Nov 9:2301011.
Garcia-Cardenas V, Hughes D, Aguilar-Palacio I, Benrimoj SI, Rabanaque MJ, Martinez-Martinez F, Malo S. (2023). Spanish translation of the ABC taxonomy for medication adherence. Res Social Adm Pharm. 2023 Sep 19(9):1292-1297. .
Jorgensen AL, Orrell C, Waitt C, Toh CH, Sekaggya-Wiltshire C, Hughes DA, Allen E, Okello E, Tatz G, Culeddu G, Asiimwe IG, Semakula JR, Mouton JP, Cohen K, Blockman M, Lamorde M, Pirmohamed M. (2023). A "Bundle of Care" to Improve Anticoagulation Control in Patients Receiving Warfarin in Uganda and South Africa: Protocol for an Implementation Study. JMIR Res Protoc. 2023 Jul 19;12:e46710. .
Marsden J, Kelleher M, Gilvarry E, Mitcheson L, Bisla J, Cape A, Cowden F, Day E, Dewhurst J, Evans R, Hardy W, Hearn A, Kelly J, Lowry N, McCusker M, Murphy C, Murray R, Myton T, Quarshie S, Vanderwaal R, Wareham A, Hughes D, Hoare Z. (2023). Superiority and cost-effectiveness of monthly extended-release buprenorphine versus daily standard of care medication: a pragmatic, parallel-group, open-label, multicentre, randomised, controlled, phase 3 trial. EClinicalMedicine. 2023 Nov 17;66:102311. .
Pijeira Perez Y, Wood E, Hughes DA. (2023). Costs of orphan medicinal products: longitudinal analysis of expenditure in Wales. Orphanet J Rare Dis. 2023 Nov 1;18(1):342. .
Sinnappah KA, Hughes DA, Stocker SL, Vrijens B, Aronson JK, Wright DFB. (2023). A framework for understanding sources of bias in medication adherence research. Br J Clin Pharmacol. 2023 Nov;89(11):3444-3453. .
Spencer LH, Hendry A, Makanjuola A, Anthony BF, Davies J, Pisavadia K, Hughes D, Fitzsimmons D, Wilkinson C, Edwards RT, Lewis R. (2023). What interventions or best practice are there to support people with Long COVID, or similar post-viral conditions or conditions characterised by fatigue, to return to normal activities: a rapid review. medRxiv. 2023 Jan.
Al-Najjar N, Bray L, Carter B, Castle AP, Collingwood A, Cook G, Crudgington H, Currier J, Dietz KC, Hardy WAS, Hiscock H, Hughes D, Morris C, Roberts D, Rouncefield-Swales A, Saron H, Spowart C, Stibbs-Eaton L, Tudur Smith C, Watson V, Whittle L, Wiggs L, Wood E, Gringras P, Pal DK. (2023). Changing Agendas on Sleep, Treatment and Learning in Epilepsy (CASTLE) Sleep-E: a protocol for a randomised controlled trial comparing an online behavioural sleep intervention with standard care in children with Rolandic epilepsy. BMJ Open. 2023 Mar 10;13(3):e065769.
Jorgensen A, Orrell C, Waitt C, Toh C-H, Sekaggya C, Hughes D, Allen E, Okello E, Tatz G, Culeddu G, Asiimwe IG, Semakula JR, Mouton JP, Cohen K, Blockman M, Lamorde M, Pirmohamed M. (2023). A 鈥渂undle of care鈥 to improve anticoagulation control in patients receiving warfarin in Uganda and South Africa: Protocol for an Implementation Study. Journal of Medical Internet Research.
Subbe C, Hughes DA, Lewis S, Holmes EA, Kalkman C, So R, Tranka S, Welch J. (2023). Value of improving patient safety: health economic considerations for rapid response systems- a rapid review of the literature and expert round table. BMJ Open. 2023 Apr 17;13 (4):e065819.
Wright DFB, Sinnappah KA, Hughes DA. (2023). Medication adherence research comes of age. Br J Clin Pharmacol. 2023 Apr 10.
Spencer LH, Hendry A, Makanjuola A, Pisavadia K, Albustami M, Anthony B, Wilkinson C, Fitzsimmons D, Hughes D, Edwards RT, Lewis R. (2023). What is the effectiveness and cost-effectiveness of interventions in reducing the harms for children and young people who have been exposed to domestic violence or abuse: a rapid review. medRxiv. 2023 May.
Noble AJ, Dixon P, Mathieson A, Ridsdale L, Morgan M, McKinlay A, Dickson J, Goodacre S, Jackson M, Morris B, Hughes D, Marson T, Holmes E. (2023). Developing feasible person-centred care alternatives to emergency department responses for adults with epilepsy: a discrete choice analysis mixed methods study. 2023 Health and Social Care Delivery Research. Available at:
2022
Sinnappah KA, Stocker SL, Chan JS, Hughes DA, Wright DFB. (2022). Clinical interventions to improve adherence to urate-lowering therapy in patients with gout: a systematic review. Int J Pharm Pract. 2022 Jun 25;30(3):215-225.
Dima AL, Allemann SS, Dunbar-Jacob J, Hughes DA, Vrijens B, Wilson IB. (2022). Methodological considerations on estimating medication adherence from self-report, electronic monitoring and electronic healthcare databases using the TEOS framework. Br J Clin Pharmacol. 2022 May 2.
Gabrio A, Plumpton C, Banerjee S, Leurent B. (2022). Linear mixed models to handle missing at random data in trial-based economic evaluations. Health Economics. 2022 Jun;31 (6):1276-1287.
Osanlou R, Walker L, Hughes DA, Burnside G, Pirmohamed M. (2022). Adverse drug reactions, multimorbidity and polypharmacy: a prospective analysis of 1 month of medical admissions. BMJ Open. 2022 Jul 4;12 (7):e055551.
Gillespie D, Couzens Z, de Bruin M, Hughes DA, Jones A, Ma R, Williams A, Wood F, Blee K, Bradshaw HS, Drayton R, Knapper C, Hood K. (2022). PrEP Use, Sexual Behaviour, and PrEP Adherence Among Men who have Sex with Men Living in Wales Prior to and During the COVID-19 Pandemic. AIDS Behav. 2022 Aug;26 (8):2746-2757.
Marsden J, Kelleher M, Hoare Z, Hughes D, Bisla J, Cape A, Cowden F, Day E, Dewhurst J, Evans R, Hearn A, Kelly J, Lowry N, McCusker M, Murphy C, Murray R, Myton T, Quarshie S, Scott G, Turner S, Vanderwaal R, Wareham A, Gilvarry E, Mitcheson L. (2022). Extended-release pharmacotherapy for opioid use disorder (EXPO): protocol for an open-label randomised controlled trial of the effectiveness and costeffectiveness of injectable buprenorphine versus sublingual tablet buprenorphine and oral liquid methadone. Trials. 2022 Aug 19;23(1):697.
Sampson C, Zamora B, Watson S, Cairns J, Chalkidou K, Cubi-Molla P, Devlin N, Garc铆a-Lorenzo B, Hughes DA, Leech AA, Towse A. (2022). Supply-Side Cost -Effectiveness Thresholds: Questions for Evidence-Based Policy. Appl Health Econ Health Policy. 2022 Sep;20(5):651-667.
Gillespie D, de Bruin M, Hughes DA, Ma R, Williams A, Wood F, Couzens Z, Jones A, Hood K. (2022). Between- and Within-Individual Sociodemographic and Psychological Determinants of PrEP Adherence Among Men Who have Sex with Men Prescribed a Daily PrEP Regimen in Wales. AIDS Behav. 2022 Nov 2:1鈥9.
Hardy WAS, Hughes DA. (2022). Methods for Extrapolating Survival Analyses for the Economic Evaluation of Advanced Therapy Medicinal Products. Hum Gene Ther. 2022 Apr 18.
Gillespie D, Wood F, Williams A, Ma R, de Bruin M, Hughes DA, Jones AT, Couzens Z, Hood K. (2022). Experiences of men who have sex with men when initiating, implementing and persisting with HIV pre-exposure prophylaxis. Health Expect. 2022 Apr 14.
Hughes DA, Bourke S, Jones A, Bhatt R, Huda S, Mutch K, Jacob A. (2022). Health utilities and costs for neuromyelitis optica spectrum disorder. Orphanet J Rare Dis. 2022 Apr 7;17(1):159.
Farmer A, Jones L, Newhouse N, Kenning C, Williams N, Chi Y, Bartlett YK, Plumpton C, McSharry J, Cholerton R, Holmes E, Robinson S, Allen J, Gudgin B, Velardo C, Rutter H, Horne R, Tarassenko L, Williams V, Locock L, Rea R, Yu LM, Hughes D, Bower P, French D. (2022). Supporting People With Type 2 Diabetes in the Effective Use of Their Medicine Through Mobile Health Technology Integrated With Clinical Care to Reduce Cardiovascular Risk: Protocol for an Effectiveness and Costeffectiveness Randomized Controlled Trial. JMIR Res Protoc. 2022 Feb 21;11 (2):e32918
Spencer LH, Hartfiel N, Hendry A, Anthony BF, Makanjuola A, Pisavadia K, Davies J, Bray N, Hughes DA, Wilkinson C, Fitzsimmons D. (2022). What innovations can address inequalities experienced by women and girls due to the COVID-19 pandemic across the different areas of life/domains: work, health, living standards, personal security, participation and education? Rapid Review. medRxiv. 2022 Jan 1.
2021
Hill-McManus D, Hughes DA. (2021). Choice of oral anticoagulant prescribed by general practices in Wales: Application of Dirichlet regression and linked data. Br J Clin Pharmacol. 2021 Dec 15. doi: 10.1111/ bcp.15183.
Marson AG, Burnside G, Appleton R, Smith D, Leach JP, Sills G, Tudur-Smith C, Plumpton CO, Hughes DA, Williamson PR, Baker G, Balabanova S, Taylor C, Brown R, Hindley D, Howell S, Maguire M, Mohanraj R, Smith PE. (2021). Lamotrigine versus levetiracetam or zonisamide for focal epilepsy and valproate versus levetiracetam for generalised and unclassified epilepsy: two SANAD II noninferiority RCTs. Health Technol Assess. 2021 Dec;25(75):1-134.
Magavern EF, Daly AK, Gilchrist A, Hughes DA. (2021). Pharmacogenomics spotlight commentary: From the United Kingdom to global populations. Br J Clin Pharmacol. 2021 May 25. doi: 10.1111/bcp.14917.
Hughes DA, Skiadas K, Fitzsimmons D, Anderson P, Heald A. (2021). Liothyronine for hypothyroidism: a candidate for disinvestment or in need of further research? A value of information analysis. BMJ Open 2021;0:e051702.
Johnson S, Marshall A, Hughes D, Holmes E, Henrich F, Nurmikko T, Sharma M, Frank B, Bassett P, Marshall A, Magerl W. (2021). Mechanistically informed non-invasive peripheral nerve stimulation for peripheral neuropathic pain: a randomised double-blind sham-controlled trial. Journal of Translational Medicine. 2021 Dec;19(1):1-5.
Heald AH, Premawardhana L, Taylor P, Okosieme O, Bangi T, Devine H, Livingston M, Javed A, Moreno GYC, Watt T, Stedman M, Dayan C, Hughes DA. (2021). Is there a role for Natural Desiccated Thyroidin the treatment of levothyroxine unresponsive hypothyroidism? Results from a Consecutive Case Series. Int J Clin Pract. 2021 Oct 9:e14967.
Culeddu G, Su L, Cheng Y, Pereira DIA, Payne RA, Powell JJ, Hughes DA. (2021). Novel oral iron therapy for iron deficiency anaemia: How to value safety in a new drug? Br J Clin Pharmacol. 2021 Sep 12.
Powell GA, Bonnett LJ, Smith CT, Hughes DA, Williamson PR, Marson AG. (2021). Using routinely recorded data in a UK RCT: a comparison to standard prospective data collection methods. Trials. 2021 Jul 5;22 (1):429.
Marson A, Burnside G, Appleton R, Smith D, Leach JP, Sills G, Tudur-Smith C, Plumpton C, Hughes DA, Williamson P, Baker GA, Balabanova S, Taylor C, Brown R, Hindley D, Howell S, Maguire M, Mohanraj R, Smith PE on behalf of the SANAD II collaborators. (2021). The SANAD II study of the effectiveness and costeffectiveness of levetiracetam, zonisamide or lamotrigine for newly diagnosed focal epilepsy: An un-blinded randomised controlled trial. Lancet 2021 pii: S0140- 6736(21)00246-4.
Marson A, Burnside G, Appleton R, Smith D, Leach JP, Sills G, Tudur-Smith C, Plumpton C, Hughes DA, Williamson P, Baker GA, Balabanova S, Taylor C, Brown R, Hindley D, Howell S, Maguire M, Mohanraj R, Smith PE on behalf of the SANAD II collaborators. (2021). The SANAD II study of the effectiveness and costeffectiveness of valproate versus levetiracetam for newly diagnosed generalised and unclassifiable epilepsy: An un-blinded randomised controlled trial. Lancet 2021 pii: S0140-6736(21)00247-6.
Thorn JC, Davies CF, Brookes ST, Noble SM, Dritsaki M, Gray E, Hughes DA, Mihaylova B, Petrou S, Ridyard C, Sach T, Wilson ECF, Wordsworth S, Hollingworth W. (2021). Content of Health Economics Analysis Plans (HEAPs) for Trial-Based Economic Evaluations: Expert Delphi Consensus Survey. Value Health. 2021 Apr;24(4):539- 547
Brogan PA, Arch B, Hickey H, Anton J, Iglesias E, Baildam E, Mahmood K, Cleary G, Moraitis E, Papadopoulou C, Beresford MW, Riley P, Demir S, Ozen S, Culeddu G, Hughes DA, Dolezalova P, Hampson LV, Whitehead J, Jayne D, Ruperto N, TudurSmith C, Eleftheriou D. (2021) Mycophenolate mofetil versus cyclophosphamide for remission induction in childhood polyarteritis nodosa: An open label, randomised, Bayesian, non-inferiority trial. Arthritis Rheumatol. 2021 Mar 24.
Cullinan J, Pheby DFH, Araja D, Berkis U, Brenna E, de Korwin JD, Gitto L, Hughes DA, Hunter RM, Trepel D, Wang-Steverding X. (2021). Perceptions of European ME/CFS Experts Concerning Knowledge and Understanding of ME/CFS among Primary Care Physicians in Europe: A Report from the European ME/ CFS Research Network (EUROMENE). Medicina (Kaunas). 2021 Feb 26;57(3):208.
Cividini S, Sinha I, Donegan S, Maden M, Culeddu G, Rose K, Fulton O, Hughes DA, Turner S, Tudur Smith C. (2021). Establishing the best STEp-up treatments for children with uncontrolled asthma despite INhaled corticosteroids (EINSTEIN): protocol for a systematic review, network meta-analysis and cost-effectiveness analysis using individual participant data (IPD). BMJ Open. 2021 Feb 5;11(2):e040528.
Wilby MJ, Best A, Wood E, Burnside G, Bedson E, Short H, Wheatley D, Hill-McManus D, Sharma M, Clark S, Baranidharan G, Price C, Mannion R, Hutchinson PJ, Hughes D, Marson AG, Williamson P. (2021). A Randomised Controlled Trial of Surgical Microdiscectomy versus Trans-foraminal Epidural Steroid Injection for sciatica of up to 1 year; the NERVES trial. The Lancet Rheumatology 2021 Mar 18;3 (5):e347-e356.
Totton N, Julious S, Hughes D, Cook J, Biggs K, Coates L, Cook A, Hewitt C, Day S. (2021). Utilising benefit-risk assessments within clinical trials-a protocol for the BRAINS project. Trials. 2021 Jan 19;22(1):68.
Hill-McManus D, Hughes DA. (2021). Combining Model-Based Clinical Trial Simulation, Pharmacoeconomics, and Value of Information to Optimize Trial Design. CPT Pharmacometrics Syst Pharmacol. 2021 Jan;10(1):75-83.
McCarroll Z, Townson J, Pickles T, Gregory JW, Playle R, Robling M, Hughes DA. (2021). Cost-effectiveness of home versus hospital management of children at onset of type 1 diabetes: the DECIDE randomised controlled trial. BMJ Open. 2021 May 19;11 (5):e043523
2020
Pheby DFH, Araja D, Berkis U, Brenna E, Cullinan J, de Korwin JD, Gitto L, Hughes DA, Hunter RM, Trepel D, Wang-Steverding X. (2020). A Literature Review of GP Knowledge and Understanding of ME/ CFS: A Report from the Socioeconomic Working Group of the European Network on ME/CFS (EUROMENE). Medicina (Kaunas). 2020 Dec 24;57(1):7.
Hughes RP, Hughes DA. (2020). Impact of Relaxing Covid-19 Social Distancing Measures on Rural North Wales: A Simulation Analysis. Front Public Health. 2020 Dec 14;8:562473
Lewis RA, Hughes D, Sutton AJ, Wilkinson C. (2020). Quantitative evidence synthesis methods for the assessment of the effectiveness of treatment sequences for clinical and economic decision making: A review and taxonomy of simplifying assumptions. Pharmacoecon. 2020 Nov 26.
Dima AL, Allemann SS, Dunbar-Jacob J, Hughes DA, Vrijens B, Wilson IB. (2020). TEOS: A framework for constructing operational definitions of medication adherence based on Timelines - Events - Objectives - Sources. Br J Clin Pharmacol. 2020 Nov 21.
Chebib N, Abou-Ayash S, Maniewicz S, Srinivasan M, Hill H, McKenna G, Holmes E, Schimmel M, Brocklehurst P, Muller F. (2020). Exploring preferred dental services of Swiss older people for when they become dependent. Swiss Dent J. 2020 Nov;130(11):876-84.
Tuleu C, Hughes DA, Clapham D, Vallet T, Ruiz F. (2020). Acceptability of generic versus innovator oral medicines: not only a matter of taste. Drug Discov Today. 2020 Nov;S1359-6446(20):30473-6
Hill-McManus D, Hughes D. (2020). Combining model-based clinical trial simulation pharmacoeconomics and value of information to optimize trial design. CPT: Pharmacometrics Syst Pharmacol. Oct 2020 20. (In press). h
Noble A, Nevitt S, Holmes E, Ridsdale L, Morgan M, Tudur-Smith C, Hughes D, Goodacre S, Marson T, Snape D. (2020). Seizure first aid training for people with epilepsy attending emergency departments and their significant others: the SAFE intervention and feasibility RCT. Southampton (UK): NIHR Journals Library. 2020 Oct; 8(39).
Albassam A, Hughes DA. (2020). What should patients do if they miss a dose? A systematic review of patient information leaflets and summaries of product characteristics. Eur J Clin Pharmacol. 2020 Sep 29.
Gillespie D, Knapper C, Hughes D, Couzens Z, Wood F, de Bruin M, Ma R, Jones AT, Williams A, Hood K. (2020). Early impact of COVID-19 social distancing measures on reported sexual behaviour of HIV pre-exposure prophylaxis users in Wales. Sex Transm Infect. 2020 Sep 23:sextrans-2020-054598
Hill-McManus D, Marshall S, Liu J, Willke RJ, Hughes DA. (2020). Linked Pharmacometric-Pharmacoeconomic Modeling and Simulation in Clinical Drug Development. Clin Pharmacol Ther. 2020 Sep
Balabanova S, Taylor C, Sills G, Burnside G, Plumpton C, Smith PEM, Appleton R, Leach JP, Johnson M, Baker G, Pirmohamed M, Hughes DA, Williamson PR, Tudur-Smith C, Marson AG. (2020). Study protocol for a pragmatic randomised controlled trial comparing the effectiveness and costeffectiveness of levetiracetam and zonisamide versus standard treatments for epilepsy: a comparison of standard and new antiepileptic drugs (SANAD-II). BMJ Open. 2020 Aug 26;10(8):e040635.
Poolman M, Roberts J, Wright S, Hendry A, Goulden N, Holmes EA, Hughes D, .. Wilkinson C. (2020). Carer administration of as-needed subcutaneous medication for breakthrough symptoms in people dying at home: the CARiAD feasibility RCT. Health Technol Assess. 2020;24 (25):1.
O鈥橮hilbin L, Woods B, Holmes E. (2020). People with dementia and caregiver preferences for digital life story work service interventions. A discrete choice experiment and digital survey. Aging Ment health. 2020 Feb;24(2):353-61.
Hughes DA. (2020). Acute chloroquine poisoning: A comprehensive experimental toxicology assessment of the role of diazepam. Br J Pharmacol. 2020 May 15.
Noble AJ, Snape D, Nevitt S, Holmes EA, Morgan M, Tudur-Smith C, Hughes DA, Buchanan M, McVicar J, MacCallum E, Goodacre S, Ridsdale L, Marson AG. (2020). Seizure First Aid Training For people with Epilepsy (SAFE) frequently attending emergency departments and their significant others: results of a UK multi-centre randomised controlled pilot trial. BMJ Open. 2020 Apr 16;10(4):e035516.
Pheby DFH, Araja D, Berkis U, Brenna E, Cullinan J, de Korwin JD, Gitto L, Hughes DA, Hunter RM, Trepel D, Wang-Steverding X. (2020). The Development of a Consistent Europe-Wide Approach to Investigating the Economic Impact of Myalgic Encephalomyelitis (ME/CFS): A Report from the European Network on ME/CFS (EUROMENE). Healthcare (Basel). 2020 Apr 7;8(2):e88.
Hughes DA. (2020). Medication adherence-Key considerations for clinical pharmacologists. Br J Clin Pharmacol. 2020 Apr;86(4):628-629.
Lloyd-Williams H, Hughes DA. (2020). A systematic review of economic evaluations of advanced therapy medicinal products. Br J Clin Pharmacol. 2020 Mar 10. https://doi.org/10.1111/ bcp.14275
Mallucci CL, Jenkinson MD, Conroy EJ, Hartley JC, Brown M, Moitt T, Dalton J, Kearns T, Griffiths MJ, Culeddu G, Solomon T, Hughes D, Gamble C. (2020). BASICS study collaborators. Silver-impregnated, antibiotic-impregnated or non-impregnated ventriculoperitoneal shunts to prevent shunt infection: the BASICS three-arm RCT. Health Technol Assess. 2020 Mar;24(17):1-114.
Farmer A, Allen J, Bartlett K, Bower P, Chi Y, French D, Gudgin B, Holmes EA, Horne R, Hughes DA, Kenning C, Locock L, McSharry J, Miles L, Newhouse N, Rea R, Riga E, Tarassenko L, Velardo C, Williams N, Williams V, Yu LM. (2020). SuMMiT-D Collaborative Group. Supporting people with type 2 diabetes in effective use of their medicine through mobile health technology integrated with clinical care (SuMMiT-D Feasibility): a randomised feasibility trial protocol. BMJ Open. Dec 29;9(12):e033504.
2019
Wood EM, Hughes DA. (2019).The New and NonTransparent Cancer Drugs Fund. Pharmacoeconomics. 2019 Dec 12.
Heald A, Livingston M, Hughes D. (2019). Management of Patients Symptomatically Unresponsive to Levothyroxine: Natural Desiccated Thyroid Extract or the Combination of Levothyroxine and Liothyronine? A Research Priority. Exp Clin Endocrinol Diabetes. 2019 Dec 9
Noble AJ, Mathieson A, Ridsdale L, Holmes EA, Morgan M, McKinlay A, Dickson JM, Jackson M, Hughes DA, Goodacre S, Marson AG. (2019). Developing patient-centred, feasible alternative care for adult emergency department users with epilepsy: protocol for the mixedmethods observational 'Collaborate' project. BMJ Open. 2019 Nov 2;9 (11):e031696.
Alshreef A, Latimer N, Tappenden P, Wong R, Hughes D, Fotheringham J, Dixon S. (2019). Statistical Methods for Adjusting Estimates of Treatment Effectiveness for Patient Nonadherence in the Context of Time-to-Event Outcomes and Health Technology Assessment: A Systematic Review of Methodological Papers. Med Decis Making. 2019 Oct 24:272989X19881654
Hughes DA. (2019). Medicines Shortages in the United Kingdom. Clin Pharmacol Ther. 2019 Oct;106(4):712.
Holmes EAF, Hughes DA. (2019). Challenges for economic evaluation of strategies to contain antimicrobial resistance. Antibiotics (Basel). 2019 Sep 27;8(4). pii: E166.
Johnson D, Hughes D, Pirmohamed M, Jorgensen A. (2019). Evidence to Support Inclusion of Pharmacogenetic Biomarkers in Randomised Controlled Trials. J Pers Med. 2019 Sep 1;9(3). pii: E42.
Mallucci CL, Jenkinson MD, Conroy EJ, Hartley JC, Brown M, Dalton J, Kearns T, Griffiths MJ, Culeddu G, Hughes D, Gamble C. (2019). For the BASICS study Collaborators. A randomised trial of antibiotic and silver catheters for ventriculoperitoneal shunts. Lancet. 2019 Sep 12. pii: S0140-6736(19)31603- 4
Moore A, Young C, Hughes DA. (2019). Health utilities and costs for Motor Neurone Disease. Value Health. 2019 Aug. DOI:
Catt H, Bodger K, Kirkham JJ, Hughes DA. (2019). Value assessment and benefit-risk modelling of biosimilar infliximab for Crohn鈥檚 disease. Pharmacoeconomics. 2019 Aug 2.
McIntyre KM, Bolton FJ, Christley RM, Cleary P, Deja E, Durie AE, Diggle PJ, Hughes D, de Lusignan S, Orton L, Radford AD, Elliot A, Smith GE, Snape DA, Stanistreet D, Vivancos R, Winstanley C, O'Brien SJ. (2019). Fully-integrated, real-time detection, diagnosis and control of community diarrhoeal disease clusters and outbreaks (the Integrate Project). JMIR Research Protocols. 2019 Jul 16
De Geest S, Zullig LL, Dunbar-Jacob J, Hughes D, Wilson IB, Vrijens B. (2019). Improving Medication Adherence Research Reporting: European Society for Patient Adherence, Compliance and Persistence Medication Adherence Reporting Guideline. J Cardiovasc Nurs. 2019 May/Jun;34(3):199-200.
Ring A, Jacoby A, Baker G, Holmes E, Hughes D, Kierans C, Marson A. (2019). What really matters? A mixed methods study of treatment preferences and priorities among people with epilepsy in the UK. Epilepsy Behav. 2019 May 6;95:181-191.
Crudgington H, Rogers M, Bray L, Carter B, Currier J, Dunkley C, Gibbon FM, Hughes D, Lyle S, Roberts D, Tudur Smith C, Gringras P, Pal DK, Morris C. (2019). Core Health Outcomes in Childhood Epilepsy (CHOICE): Development of a core outcome set using systematic review methods and a Delphi survey consensus. Epilepsia. 2019 May;60(5):857-871.
Ramanan AV, Dick AD, Jones AP, Hughes DA, McKay A, RosalaHallas A, Williamson PR, Hardwick B, Hickey H, Rainford N, Hickey G, Kolamunnage-Dona R, Culeddu G, Plumpton C, Wood E, Compeyrot-Lacassagne S, Woo P, Edelsten C, Beresford MW. (2019). Adalimumab in combination with methotrexate for refractory uveitis associated with juvenile idiopathic arthritis: a RCT. Health Technol Assess. 2019 Apr;23 (15):1-140.
Blair JC, McKay A, Ridyard C, Thornborough K, Bedson E, Peak M, Didi M, Annan F, Gregory JW, Hughes DA, (2019). Gamble C for the SCIPI investigators. Continuous Subcutaneous Insulin Infusion Compared to Multiple Daily Injection Regimens in Children and Young People at Diagnosis of Type I Diabetes: A Pragmatic Randomised Controlled Trial and Economic Evaluation. BMJ. 2019 Apr 3;365:l1226
Catt H, Hughes D, Kirkham JJ, Bodger K. (2019). Systematic review: Outcomes and adverse events from randomised trials in Crohn鈥檚 disease. Aliment Pharmacol Ther. 2019 Apr;49(8):978- 996
De Geest S, Zullig LL, Dunbar-Jacob J, Hughes D, Wilson IB, Vrijens B. (2019). Improving medication adherence research reporting: ESPACOMP Medication Adherence Reporting Guideline (EMERGE). Eur J Cardiovasc Nurs. 2019 Apr;18(4):258-259
Hill-McManus D, Marshall S, Soto E, Hughes D. (2019). Integration of pharmacometrics and pharmacoeconomics to quantify the value of improved forgiveness to non-adherence: A case study of novel xanthine oxidase inhibitors for gout. Clin Pharmacol Ther. 2019 Apr 16.
Hughes DA, Culeddu G, Plumpton C, Wood E, Dick AD, Beresford MW, Ramanan AV. (2019). Reply. Ophthalmology. 2019 Mar;126(3):e24-e25
Hughes DA, Culeddu G, Plumpton CO, Wood E, Dick AD, Jones AP, McKay A, Williamson PR, Compeyrot Lacassagne S, Hardwick B, Hickey H, Woo P, Beresford MW, Ramanan AV. (2019). Cost-Effectiveness Analysis of Adalimumab for the Treatment of Uveitis Associated with Juvenile Idiopathic Arthritis. Ophthalmology. 2019 Mar;126(3):415-424.
Poolman M, Roberts J, Byrne A, Perkins P, Hoare Z, Nelson A, Hiscock J, Hughes D, Foster B, O'Connor J, Reymond L, Healy S, Roberts R, Wee B, Lewis P, Johnstone R, Roberts S, Holmes E, Wright S, Hendry A, Wilkinson C. (2019). CARer-ADministration of as-needed subcutaneous medication for breakthrough symptoms in homebased dying patients (CARiAD): study protocol for a UK-based open randomised pilot trial. Trials. 2019 Feb 7;20(1):105
2018
Philbin L, Woods R, Holmes EAF. (2018). People with dementia and caregiver preferences for digital life story work service interventions: A discrete choice experiment and digital survey. Aging Mental Health, 2018 (In press)
Holmes E, Bourke S, Plumpton C. (2018). Attitudes towards epilepsy in the UK population: Results from a 2018 national survey. Seizure. 2018 Dec 18;65:12-19.
Holmes EAF, Harris SD, Hughes A, Craine N, Hughes DA. (2018). Cost-Effectiveness Analysis of the Use of Point-of-Care C-Reactive Protein Testing to Reduce Antibiotic Prescribing in Primary Care. Antibiotics (Basel). 2018;7(4). pii: E106.
Hill-McManus D, Marshall S, Soto E, Lane S, Hughes D. (2018). Impact of Non-Adherence and Flare Resolution on the Cost-Effectiveness of Treatments for Gout: Application of a Linked Pharmacometric/Pharmacoeconomic Model. Value Health. 2018 Dec;21 (12):1373-1381.
Plumpton CO, Pirmohamed M, Hughes DA. (2018). Cost-effectiveness of panel tests for multiple pharmacogenes associated with adverse drug reactions: An evaluation framework. Clin Pharmacol Ther. 2018 Nov 22.
Moore A, Young CA, Hughes DA. (2018). Mapping ALSFRS-R and ALSUI to EQ-5D in Patients with Motor Neuron Disease. Value Health. 2018 Nov;21(11):1322-1329.
Hughes DA, Culeddu G, Plumpton CO, Wood E, Dick AD, Jones AP, McKay A, Williamson PR, Compeyrot Lacassagne S, Hardwick B, Hickey H, Woo P, Beresford MW, Ramanan AV. (2018). Cost-Effectiveness Analysis of Adalimumab for the Treatment of Uveitis Associated with Juvenile Idiopathic Arthritis. Ophthalmology. 2018 Oct 16. pii: S0161- 6420(18)31146-1.
Jenkinson MD, Weber DC, Haylock BJ, Sherratt FC, Young B, Weller M, Bulbeck H, Culeddu G, Hughes DA, Brain A, Das K, Preusser M, Francis P, Gamble C. (2018). Letter to the Editor. Phase III randomized controlled trials are essential to properly evaluate the role of radiotherapy in WHO grade II meningioma. J Neurosurg. 2018 Oct;129 (4):1104-1105.
Holmes EAF, Plumpton C, Baker GA, Jacoby A, Ring A, Williamson P, Marson A, Hughes DA. (2018). Patient-Focused Drug Development Methods for Benefit-Risk Assessments: A Case Study Using a Discrete Choice Experiment for Antiepileptic Drugs. Clin Pharmacol Ther. 2018 Sep 11.
Wilby MJ, Hopkins C, Bedson E, Howlin S, Burnside G, Conroy EJ, Hughes DA, Sharma M, Marson A, Clark SR, Williamson P. (2018). Nerve root block versus surgery (NERVES) for the treatment of radicular pain secondary to a prolapsed intervertebral disc herniation: study protocol for a multi-centre randomised controlled trial. Trials. 2018 Sep 5;19 (1):475.
Blair J, McKay A, Ridyard C, Thornborough K, Bedson E, Peak M, Didi M, Annan F, Gregory JW, Hughes D, Gamble C. (2018). Continuous subcutaneous insulin infusion versus multiple daily injections in children and young people at diagnosis of type 1 diabetes: the SCIPI RCT. Health Technol Assess. 2018 Aug;22 (42):1-112
Williams NH, Jenkins A, Goulden N, Hoare Z, Hughes DA, Wood E, Foster NE, Walsh D, Carnes D, Sparkes V, Hay EM, Isaacs J, Konstantinou K, Morrissey D, Karppinen J, Genevay S, Wilkinson C. (2018). Lessons learnt from a discontinued randomised controlled trial: adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica (Subcutaneous Injection of Adalimumab Trial compared with Control: SCIATiC). Trials. 2018 Jul 31;19(1):408.
De Geest S, Zullig LL, Dunbar-Jacob J, Helmy R, Hughes DA, Wilson IB, Vrijens B. (2018). ESPACOMP Medication Adherence Reporting Guideline (EMERGE). Ann Intern Med. 2018 Jun 26.
Thorn JC, Brookes ST, Ridyard C, Riley R, Hughes DA, Wordsworth S, Noble SM, Thornton G, Hollingworth W. (2018). Core Items for a Standardized Resource Use Measure: Expert Delphi Consensus Survey. Value Health. 2018;21(6):640-649.
Swift B, Jain L, White C, Chandrasekaran V, Bhandari A, Hughes DA, Jadhav PR. (2018). Innovation at the Intersection of Clinical Trials and RealWorld Data Science to Advance Patient Care. Clin Transl Sci. 2018 May 16.
Hughes DA, Plumpton CO. (2018). Rare disease prevention and treatment: the need for a level playing field. Pharmacogenomics. 2018;19(3):243-247.
Hughes DA. (2018). Economics of Pharmacogenetic-Guided Treatments: Underwhelming or Overstated? Clin Pharmacol Ther. 2018;103 (5):749-751.
Varnava A, Bracchi R, Samuels K, Hughes DA, Routledge PA. (2018). New Medicines in Wales: The All Wales Medicines Strategy Group (AWMSG) Appraisal Process and Outcomes. Pharmacoeconomics. 2018;36(5):613-624.
Chim L, Salkeld G, Kelly PJ, Lipworth W, Hughes DA, Stockler MR. (2018). Community views on factors affecting medicines resource allocation: cross-sectional survey of 3080 adults in Australia. Aust Health Rev. 2018 Apr 19.
Roberts JL, Din NU, Williams M, Hawkes CA, Charles JM, Hoare Z, Morrison V, Alexander S, Lemmey A, Sackley C, Logan P, Wilkinson C, Rycroft-Malone J, Williams NH. Development of an evidence-based complex intervention for community rehabilitation of patients with hip fracture using realist review, survey and focus groups. BMJ open. 2017;7(10):e014362
Bourke SM, Plumpton CO, Hughes DA. Societal Preferences for Funding Orphan Drugs in the United Kingdom: An Application of Person Trade-Off and Discrete Choice Experiment Methods. Value Health. 2018;21(5):538-546.
2017
Hill-McManus D, Soto E, Marshall S, Lane S, Hughes D. (2017). Impact of non-adherence on the safety and efficacy of uric acidlowering therapies in the treatment of gout. Br J Clin Pharmacol. 2017 Sep 9.
Ridyard CH, Plumpton CO, Gilbert RE, Hughes DA. (2017). Cost-Effectiveness of Pediatric Central Venous Catheters in the UK: A Secondary Publication from the CATCH Clinical Trial. Front Pharmacol. 2017 Sep 19;8:644
Hagemi A, Plumpton C, Hughes DA. (2017). Renal transplant patients鈥 preference for the supply and delivery of immunosuppressants in Wales: a discrete choice experiment. BMC Nephrol. 2017 Oct 2;18(1):305.
Powell GA, Bonnett LJ, Tudur-Smith C, Hughes DA, Williamson PR, Marson AG. (2017). Using routinely recorded data in the UK to assess outcomes in a randomised controlled trial: The Trials of Access. Trials. 2017 Aug 23;18(1):389.
Morris C, Dunkley C, Gibbon FM, Currier J, Roberts D, Rogers M, Crudgington H, Bray L, Carter B, Hughes D, Tudur Smith C, et al. (2017). Core Health Outcomes In Childhood Epilepsy (CHOICE): protocol for the selection of a core outcome set. Trials. 2017 Nov 28;18(1):572
Williams NH, Jenkins A, Goulden N, Hoare Z, Hughes DA, Wood E, Foster NE, Walsh DA, Carnes D, Sparkes V, Hay EM, Isaacs J, Konstantinou K, Morrissey D, Karppinen J, Genevay S, Wilkinson C. (2017). Subcutaneous Injection of Adalimumab Trial compared with Control (SCIATiC): a randomised controlled trial of adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica. Health Technol Assess. 2017 Oct;21(60):1-180.
Plumpton CO, Alfirevic A, Pirmohamed M, Hughes DA. (2017). Cost effectiveness analysis of HLA-B*58:01 genotyping prior to initiation of allopurinol for gout. Rheumatology (Oxford). 2017 Oct 1;56(10):1729-1739
Hulbert-Williams N, Plumpton C, Flowers P, McHugh R, Neal R, Semlyen J, Storey L. (2017). The cancer care experiences of gay, lesbian and bisexual patients: A secondary analysis of data from the UK Cancer Patient Experience Survey. Eur J Cancer Care. 2017
Davies EH, Fulton E, Brook D, Hughes DA. (2017). Affordable orphan drugs: a role for not-for-profit organizations. Br J Clin Pharmacol. 2017;83(7):1595-1601
Prayle AP, Cox T, Smith SJ, Rycroft-Malone J, Thomas KS, Hughes DA, Smyth AR. (2017). Do guidelines for treating chest disease in children use Cochrane Reviews effectively? A systematic review. Thorax. 2017.
Ramanan AV, Dick AD, Jones AP, McKay A, Williamson PR, Compeyrot-Lacassagne S, Hardwick B, Hickey H, Hughes D, Woo P, Benton D, Edelsten C, Beresford MW; SYCAMORE Study Group. (2017). Adalimumab plus Methotrexate for Uveitis in Juvenile Idiopathic Arthritis. N Engl J Med. 2017;376(17):1637-1646
Chim L, Salkeld G, Kelly P, Lipworth W, Hughes DA, Stockler MR. (2017). Societal perspective on access to publicly subsidised medicines: A cross sectional survey of 3080 adults in Australia. PLoS One. 2017;12(3):e017297
2016
Johnson S, Richey R, Holmes E, Hughes D, Goebel A. (2016). A randomised, patient-assessor blinded, sham-controlled trial of external non-invasive peripheral nerve stimulation for chronic neuropathic pain following peripheral nerve injury (EN-PENS trial): study protocol for a randomised controlled trial. Trials. 2016;17(1):57
Moore A, Young C, Hughes DA. (2016). Economic studies in Motor Neurone Diseases: A systematic methodological review. Pharmacoeconomics 2016.
Hughes DA, Poletti-Hughes J. (2016). Profitability and Market Value of Orphan Drug Companies: A Retrospective, Propensity-Matched Case-Control Study. PLoS One. 2016 Oct 21;11(10):e0164681
Mulhern B, Pink J, Rowen D, Borghs S, Butt T, Hughes D, Marson A, Brazier J. (2016) Comparing generic and condition-specific preferencebased measures in epilepsy: EQ-5D-3L and NEWQOL-6D. Value Health 2016;
Verhoef TI, Redekop WK, Langenskiold S, Kamali F, Wadelius M, Burnside G, Maitlandvan der Zee AH, Hughes DA, Pirmohamed M. (2016). Cost-effectiveness of pharmacogenetic-guided dosing of warfarin in the United Kingdom and Sweden. Pharmacogenomics J. 2016 Oct;16(5):478-84
Hughes D, Charles J, Dawoud D, Edwards RT, Holmes E, Jones C, Parham P, Plumpton C, Ridyard C, Lloyd-Williams H, Wood E, Yeo ST. (2016). Conducting Economic Evaluations Alongside Randomised Trials: Current Methodological Issues and Novel Approaches. PharmacoEconomics. 2016.
Plumpton CO, Morris T, Hughes D, White I. (2016). Multiple imputation of multiple multi-item scales when a full imputation model is infeasible. BMC Research Notes. 2016; 9:45
Gilbert RE, Mok Q, Dwan K, Harron K, Moitt T, Millar M, Ramnarayan P, Tibby SM, Hughes D, Gamble C; CATCH trial investigators. (2016). Impregnated central venous catheters for prevention of bloodstream infection in children (the CATCH trial): a randomised controlled trial. Lancet. 2016 Apr 23;387 (10029):1732-42
Plumpton CO, Roberts D, Pirmohamed M, Hughes DA. (2016). A Systematic Review of Economic Evaluations of Pharmacogenetic Testing for Prevention of Adverse Drug Reactions 2016.
Holmes EA, Morrison VL, Hughes DA. (2016). What influences persistence with medicines? A multinational discrete choice experiment of 2549 patients. British Journal of Clinical Pharmacology. 2016
Breckenridge A, Hughes D. Prof. John Urquhart. Br J Clin Pharmacol. 2016 May 2.
Ridyard CH, Dawoud DMM, Tuersley LV, Hughes DA. (2016). A Systematic Review of Patients鈥 Perspectives on the Subcutaneous Route of Medication Administration. Patient. 2016.
Hughes D, Charles J, Dawoud D, Edwards RT, Holmes E, Jones C, Parham P, Plumpton C, Ridyard C, Lloyd-Williams H, Wood E, Yeo ST. (2016). Conducting economic evaluations alongside randomised trials: Current methodological issues. Pharmacoeconomics. 2016 Jan.
2015
Ridyard CH, Hughes DA, DIRUM Team. (2015). Review of resource-use measures in UK economic evaluations. In: PSSRU Unit Costs of Health and Social Care 2015: 22-31. Compiled by Lesley Curtis and Amanda Burns. University of Kent 2015
Jenkinson MD, Javadpour M, Haylock BJ, Young B, Gillard H, Vinten J, Bulbeck H, Das K, Farrell M, Looby S, Hickey H, Preusser M, Mallucci CL, Hughes D, Gamble C, Weber DC. (2015). The ROAM/EORTC-1308 trial: Radiation versus Observation following surgical resection of Atypical Meningioma: study protocol for a randomised controlled trial. Trials. 2015 Nov 14;16:519.
Powell G, Holmes EA, Plumpton CO, Ring A, Baker GA, Jacoby A, Pirmohamed M, Marson AG, Hughes DA. (2015). Pharmacogenetic testing prior to carbamazepine treatment of epilepsy: patients' and physicians' preferences for testing and service delivery. Br J Clin Pharmacol. 2015 Nov;80(5):1149- 59
Richter T, Nestler-Parr S, Babela R, Khan ZM, Tesoro T, Molsen E, Hughes DA. (2015). International Society for Pharmacoeconomics and Outcomes Research Rare Disease Special Interest Group. Rare Disease Terminology and Definitions-A Systematic Global Review: Report of the ISPOR Rare Disease Special Interest Group. Value Health. 2015 Sep;18(6):906-14.
Blair J, Gregory JW, Hughes D, Ridyard CH, Gamble C, McKay A, Didi M, Thornborough K, Bedson E, Awoyale L, Cwiklinski E, Peak M. (2015). Study protocol for a randomised controlled trial of insulin delivery by continuous subcutaneous infusion compared to multiple daily injections. Trials. 2015 Apr;16:163.
Ridyard CH, Hughes DA, DIRUM Team. (2015). Taxonomy for methods of resource use measurement. Health Econ. 2015 Mar;24(3):372-8.
Blair J, Gregory JW, Hughes D, Ridyard CH, Gamble C, McKay A, Didi M, Thornborough K, Bedson E, Awoyale L, Cwiklinski E, Peak M. (2015). Study protocol for a randomised controlled trial of insulin delivery by continuous subcutaneous infusion compared to multiple daily injections. Trials. 2015 Apr 16; 16(1):163.
L枚tsch F, Hackenberg LA, Groger M, Rehman K, Morrison V, Holmes E, Parveen S, Plumpton C, Clyne W, de Geest S, Dobbels F, Vrijens B, Kardas P, Hughes D, Ramharter M. (2015). Adherence of patients to long-term medication: A cross sectional study of antihypertensive regimens in Austria. Wien Klin Wochenschr. 2015 May;127 (9-10):379-84
Hughes DA, Wood EM, Tuersley L. (2015). NICE recommendations: why no disinvestment recommendations to offset investment decisions? BMJ. 2015 May 19;350:h2656.
Plumpton CO, Brown I, Reuber M, Marson T, Hughes DA. (2015). Economic evaluation of a behavior-modifying intervention to enhance antiepileptic drug adherence. Epilepsy Behav. 2015 Apr;45:180-6.
Plumpton CO, Yip VLM, Alfirevic A, Marson AG, Pirmohamed M, Hughes DA. (2015) Cost effectiveness of screening for HLA-A*31:01 prior to initiation of carbamazepine in epilepsy. Epilepsia 2015
Morrison VL, Holmes EAF, Parveen S, Plumpton CO, Clyne W, De Geest S, Dobbels F, Vrijens B, Kardas P, Hughes DA. (2015). Predictors of self-reported adherence to antihypertensive medicines: A multi-national, crosssectional survey. Value in Health 2015;
Roberts E, Dawoud DD, Hughes DA, Cefai C. (2015). Evaluation of a Consultant Audit and Feedback Programme to Improve the Quality of Antimicrobial Prescribing in Acute Medical Admissions. Int J Pharm Pract. 2015
Parham P, Hughes D. (2015). Climatic influences on the cost-effectiveness of vector-based interventions against malaria in elimination scenarios. Philosophical Transactions B. 2015
2014
Holmes EA, Hughes DA, Morrison VL. (2014). Predicting Adherence to Medications Using Health Psychology Theories: A Systematic Review of 20 Years of Empirical Research. Value Health. 2014 Dec;17(8):863-876.
Schaffer S K, Sussex J, Hughes D and Devlin N. (2014). Opportunity costs of implementing NICE decisions in NHS Wales. Research Paper 14/02. 2014. London: Office of Health Economics
Mulhern B, Rowen D, Snape D, Jacoby A, Marson T, Hughes D, Baker G, Brazier J. (2014) Valuations of epilepsy-specific health states: a comparison of patients with epilepsy and the general population. Epilepsy Behav. 2014 May 15;36C:12-1
Sutton S, Kinmonth AL, Hardeman W, Hughes D, Boase S, Prevost AT, Kellar I, Graffy J, Griffin S, Farmer A. (2014). Does Electronic Monitoring Influence Adherence to Medication? Randomized Controlled Trial of Measurement Reactivity. Ann Behav Med. 2014 Feb 27.
Bedson E, Bell D, Carr D, Carter B, Hughes D, Jorgensen A, et al. (2014). Folate Augmentation of Treatment - Evaluation for Depression (FolATED): randomised trial and economic evaluation. Health Technol Assess 2014;18(48)
Ridyard CH, Hughes DA; DIRUM Team. (2014). Taxonomy for methods of resource use measurement. Health Econ. 2014.
Ramanan AV, Dick AD, Benton D, Compeyrot-Lacassagne S, Dawoud D, Hardwick B, Hickey H, Hughes D, Jones A, Woo P, Edelsten C, Beresford MW; (2014). SYCAMORE Trial Management Group. A randomised controlled trial of the clinical effectiveness, safety and cost-effectiveness of adalimumab in combination with methotrexate for the treatment of juvenile idiopathic arthritis associated uveitis (SYCAMORE Trial). Trials. 2014 Jan 9;15(1):14.
Jenkinson MD, Gamble C, Hartley JC, Hickey H, Hughes D, Blundell M, Griffiths MJ, Solomon T, Mallucci CL. (2014). The British antibiotic and silver-impregnated catheters for ventriculoperitoneal shunts multi-centre randomised controlled trial (the BASICS trial): study protocol. Trials. 2014 Jan 3;15(1):4.
